Specific Recognition of a Single-stranded RNA Sequence by a Synthetic Antibody Fragment

Antibodies that bind RNA represent an unrealized source of reagents for synthetic biology and for characterizing cellular transcriptomes. However, facile access to RNA binding antibodies requires engineering of effective Fab libraries guided by knowledge of the principles that govern RNA recognition...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Shao, Yaming, Huang, Hao, Qin, Daoming, Li, Nan-Sheng, Koide, Akiko, Staley, Jonathan P., Koide, Shohei, Kossiakoff, Anthony A., Piccirilli, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5178103/
https://ncbi.nlm.nih.gov/pubmed/27593161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.08.029
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