Specific Recognition of a Single-stranded RNA Sequence by a Synthetic Antibody Fragment

Antibodies that bind RNA represent an unrealized source of reagents for synthetic biology and for characterizing cellular transcriptomes. However, facile access to RNA binding antibodies requires engineering of effective Fab libraries guided by knowledge of the principles that govern RNA recognition...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Biol
Prif Awduron: Shao, Yaming, Huang, Hao, Qin, Daoming, Li, Nan-Sheng, Koide, Akiko, Staley, Jonathan P., Koide, Shohei, Kossiakoff, Anthony A., Piccirilli, Joseph A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5178103/
https://ncbi.nlm.nih.gov/pubmed/27593161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.08.029
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