Specific Recognition of a Single-stranded RNA Sequence by a Synthetic Antibody Fragment

Antibodies that bind RNA represent an unrealized source of reagents for synthetic biology and for characterizing cellular transcriptomes. However, facile access to RNA binding antibodies requires engineering of effective Fab libraries guided by knowledge of the principles that govern RNA recognition...

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Vydáno v:J Mol Biol
Hlavní autoři: Shao, Yaming, Huang, Hao, Qin, Daoming, Li, Nan-Sheng, Koide, Akiko, Staley, Jonathan P., Koide, Shohei, Kossiakoff, Anthony A., Piccirilli, Joseph A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5178103/
https://ncbi.nlm.nih.gov/pubmed/27593161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.08.029
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