Specific Recognition of a Single-stranded RNA Sequence by a Synthetic Antibody Fragment

Antibodies that bind RNA represent an unrealized source of reagents for synthetic biology and for characterizing cellular transcriptomes. However, facile access to RNA binding antibodies requires engineering of effective Fab libraries guided by knowledge of the principles that govern RNA recognition...

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Veröffentlicht in:J Mol Biol
Hauptverfasser: Shao, Yaming, Huang, Hao, Qin, Daoming, Li, Nan-Sheng, Koide, Akiko, Staley, Jonathan P., Koide, Shohei, Kossiakoff, Anthony A., Piccirilli, Joseph A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5178103/
https://ncbi.nlm.nih.gov/pubmed/27593161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.08.029
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