T Cell Receptor-Like Recognition of Tumor In Vivo by Synthetic Antibody Fragment

A major difficulty in treating cancer is the inability to differentiate between normal and tumor cells. The immune system differentiates tumor from normal cells by T cell receptor (TCR) binding of tumor-associated peptides bound to Major Histocompatibility Complex (pMHC) molecules. The peptides, der...

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Main Authors: Miller, Keith R., Koide, Akiko, Leung, Brenda, Fitzsimmons, Jonathan, Yoder, Bryan, Yuan, Hong, Jay, Michael, Sidhu, Sachdev S., Koide, Shohei, Collins, Edward J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423377/
https://ncbi.nlm.nih.gov/pubmed/22916301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043746
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