Crystal Structure of the Catalytic Core of an RNA-Polymerase Ribozyme

Primordial organisms of the putative RNA world would have required polymerase ribozymes able to replicate RNA. Known ribozymes with polymerase activity best approximating that needed for RNA replication contain at their catalytic core the class I RNA ligase, an artificial ribozyme with a catalytic r...

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Bibliographic Details
Main Authors: Shechner, David M., Grant, Robert A., Bagby, Sarah C., Koldobskaya, Yelena, Piccirilli, Joseph A., Bartel, David P.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978776/
https://ncbi.nlm.nih.gov/pubmed/19965478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1174676
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