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Crystal Structure of the Catalytic Core of an RNA-Polymerase Ribozyme

Primordial organisms of the putative RNA world would have required polymerase ribozymes able to replicate RNA. Known ribozymes with polymerase activity best approximating that needed for RNA replication contain at their catalytic core the class I RNA ligase, an artificial ribozyme with a catalytic r...

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Detalhes bibliográficos
Main Authors: Shechner, David M., Grant, Robert A., Bagby, Sarah C., Koldobskaya, Yelena, Piccirilli, Joseph A., Bartel, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978776/
https://ncbi.nlm.nih.gov/pubmed/19965478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1174676
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