The autophagic tumor stroma model of cancer or “battery-operated tumor growth”: A simple solution to the autophagy paradox

The role of autophagy in tumorigenesis is controversial. Both autophagy inhibitors (chloroquine) and autophagy promoters (rapamycin) block tumorigenesis by unknown mechanism(s). This is called the “Autophagy Paradox.” We have recently reported a simple solution to this paradox. We demonstrated that...

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Dades bibliogràfiques
Autors principals: Martinez-Outschoorn, Ubaldo E, Whitaker-Menezes, Diana, Pavlides, Stephanos, Chiavarina, Barbara, Bonuccelli, Gloria, Trimmer, Casey, Tsirigos, Aristotelis, Migneco, Gemma, Witkiewicz, Agnieszka K, Balliet, Renee, Mercier, Isabelle, Wang, Chengwang, Flomenberg, Neal, Howell, Anthony, Lin, Zhao, Caro, Jaime, Pestell, Richard G, Sotgia, Federica, Lisanti, Michael P
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2010
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055183/
https://ncbi.nlm.nih.gov/pubmed/21051947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.21.13817
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