Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: Similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling"

Caveolin-1 (-/-) null stromal cells are a novel genetic model for cancer-associated fibroblasts and myofibroblasts. Here, we used an unbiased informatics analysis of transcriptional gene profiling to show that Cav-1 (-/-) bone-marrow derived stromal cells bear a striking resemblance to the activated...

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Detalhes bibliográficos
Main Authors: Pavlides, Stephanos, Tsirigos, Aristotelis, Vera, Iset, Flomenberg, Neal, Frank, Philippe G., Casimiro, Mathew C., Wang, Chenguang, Pestell, Richard G., Martinez-Outschoorn, Ubaldo E., Howell, Anthony, Sotgia, Federica, Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881509/
https://ncbi.nlm.nih.gov/pubmed/20442453
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