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MODELING OF THE ENDOSOMOLYTIC ACTIVITY OF HA2-TAT PEPTIDES WITH RED BLOOD CELLS AND GHOSTS

HA2-TAT is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. This chimeric peptide is engineered to induce the cellular uptake of macromolecules into endosomes via the TAT moiety and to respond to the acidif...

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Detalhes bibliográficos
Main Authors: Lee, Ya-Jung, Johnson, Gregory, Pellois, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053598/
https://ncbi.nlm.nih.gov/pubmed/20704453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1008408
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