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Protein delivery into live cells by incubation with an endosomolytic agent
We report on how a dimer of the cell-penetrating peptide TAT, dfTAT, penetrates live cells by escaping from endosomes with a particularly high efficiency. By mediating endosomal leakage, dfTAT also delivers proteins into cultured cells after a simple co-incubation procedure. Cytosolic delivery is ac...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131206/ https://ncbi.nlm.nih.gov/pubmed/24930129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2998 |
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