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An l- to d-Amino Acid Conversion in an Endosomolytic Analog of the Cell-penetrating Peptide TAT Influences Proteolytic Stability, Endocytic Uptake, and Endosomal Escape

Cell-penetrating peptides (CPPs) are well established as delivery agents for otherwise cell-impermeable cargos. CPPs can also theoretically be used to modulate intracellular processes. However, their susceptibility to proteolytic degradation often limits their utility in these applications. Previous...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Najjar, Kristina, Erazo-Oliveras, Alfredo, Brock, Dakota J., Wang, Ting-Yi, Pellois, Jean-Philippe
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247658/
https://ncbi.nlm.nih.gov/pubmed/27923812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.759837
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