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Generation of Endosomolytic Reagents by Branching of Cell-Penetrating Peptides: Tools for the Delivery of Bioactive Compounds to Live Cells in Cis or Trans

We describe the synthesis and cellular delivery properties of multivalent and branched delivery systems consisting of cell-penetrating peptides assembled onto a peptide scaffold using Native Chemical Ligation. A trimeric delivery system presenting three copies of the prototypical cell-penetrating pe...

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Detalhes bibliográficos
Main Authors: Angeles-Boza, Alfredo M., Erazo-Oliveras, Alfredo, Lee, Ya-Jung, Pellois, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074029/
https://ncbi.nlm.nih.gov/pubmed/21043514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100130r
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