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A HA2-Fusion Tag Limits the Endosomal Release of its Protein Cargo Despite Causing Endosomal Lysis (†)
BACKGROUND: Protein transduction domains (PTDs) can be fused to a protein to render it cell-permeable. The delivery efficiencies of PTDs are, however, often poor because PTD-protein conjugates cannot escape from endosomes. A potential solution this problem consists in adding HA2 analogs to the PTD-p...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128663/ https://ncbi.nlm.nih.gov/pubmed/21664431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2011.05.013 |
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