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Triterpene Derivatives that Inhibit Human Immunodeficiency Virus Type 1 Replication
Triterpene derivatives were analyzed for anti-HIV-1 activity and for cellular toxicity. Betulinic aldehyde, betulinic nitrile, and morolic acid derivatives were identified to have anti-HIV-1 activity. These derivatives inhibit a late step in virus replication, likely virus maturation.
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3053071/ https://ncbi.nlm.nih.gov/pubmed/21084190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.10.078 |
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