Triterpene derivatives that block entry of human immunodeficiency virus type 1 into cells.

A series of triterpene compounds characterized by a stringent structure-activity relationship were identified as potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) replication. Currently studied botulinic derivatives have 50% inhibitory concentrations (IC50) against HIV-1...

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Autors principals: Mayaux, J F, Bousseau, A, Pauwels, R, Huet, T, Hénin, Y, Dereu, N, Evers, M, Soler, F, Poujade, C, De Clercq, E
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC43620/
https://ncbi.nlm.nih.gov/pubmed/8170948
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