Selective inhibition of human immunodeficiency virus type 1 replication by the (-) but not the (+) enantiomer of gossypol.

The (-) enantiomer of gossypol but not the (+) enantiomer had good antiviral activity in peripheral blood mononuclear cells against human immunodeficiency virus type 1 at a concentration more than 20-fold lower than that required for cytotoxicity; however, in H9 cells the (-) enantiomer, although mo...

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Autores principales: Lin, T S, Schinazi, R, Griffith, B P, August, E M, Eriksson, B F, Zheng, D K, Huang, L A, Prusoff, W H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC172840/
https://ncbi.nlm.nih.gov/pubmed/2619282
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