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Selective inhibition of human immunodeficiency virus type 1 replication by the (-) but not the (+) enantiomer of gossypol.

The (-) enantiomer of gossypol but not the (+) enantiomer had good antiviral activity in peripheral blood mononuclear cells against human immunodeficiency virus type 1 at a concentration more than 20-fold lower than that required for cytotoxicity; however, in H9 cells the (-) enantiomer, although mo...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Lin, T S, Schinazi, R, Griffith, B P, August, E M, Eriksson, B F, Zheng, D K, Huang, L A, Prusoff, W H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172840/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2619282/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.12.2149
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