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Thalidomide inhibits the replication of human immunodeficiency virus type 1.

Thalidomide, a selective inhibitor of tumor necrosis factor alpha (TNF-alpha) synthesis, suppresses the activation of latent human immunodeficiency virus type 1 (HIV-1) in a monocytoid (U1) line. The inhibition is dose dependent and occurs after exposure of the cells to recombinant TNF-alpha, phorbo...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Makonkawkeyoon, S, Limson-Pobre, R N, Moreira, A L, Schauf, V, Kaplan, G
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1993
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46849/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327469/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.5974
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