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Derivation of a biologically contained replication system for human immunodeficiency virus type 1.

Human immunodeficiency virus type 1 (HIV-1) proviral mutants that lack viral regulatory genes are unable to replicate unless rescued by complementation in trans. Structurally intact virus can be produced by infecting recombinant cell lines expressing the deficient genes. A HIV-1 mutant functionally...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Chen, H, Boyle, T J, Malim, M H, Cullen, B R, Lyerly, H K
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1992
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49774/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502183/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7678
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