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Derivation of a biologically contained replication system for human immunodeficiency virus type 1.

Human immunodeficiency virus type 1 (HIV-1) proviral mutants that lack viral regulatory genes are unable to replicate unless rescued by complementation in trans. Structurally intact virus can be produced by infecting recombinant cell lines expressing the deficient genes. A HIV-1 mutant functionally...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Chen, H, Boyle, T J, Malim, M H, Cullen, B R, Lyerly, H K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49774/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502183/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7678
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