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Sonic Hedgehog-induced Proliferation Requires Specific Gα Inhibitory Proteins
Proliferation of cerebellar granular neuronal precursors (CGNPs) is mediated by Sonic Hedgehog (Shh), which activates the Patched and Smoothened (Smo) receptor complex. Although its protein sequence suggests that Smo is a G protein coupled receptor (GPCR), the evidence that this receptor utilizes he...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048693/ https://ncbi.nlm.nih.gov/pubmed/21209076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178772 |
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