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The G protein Gα(s) acts as a tumor suppressor in sonic hedgehog signaling-driven tumorigenesis

G protein-coupled receptors (GPCRs) are critical players in tumor growth and progression. The redundant roles of GPCRs in tumor development confound effective treatment; therefore, targeting a single common signaling component downstream of these receptors may be efficacious. GPCRs transmit signals...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Rao, Rohit, Salloum, Ralph, Xin, Mei, Lu, Q. Richard
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889240/
https://ncbi.nlm.nih.gov/pubmed/27052725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1164371
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