Cre/LoxP-HBV plasmids generating recombinant covalently closed circular DNA genome upon transfection

nork Kruse, Robert L., Legras, Xavier, Barzi, Mercedes
Argitaratua izan da Virus Res (2020)

Sonic Hedgehog-induced Proliferation Requires Specific Gα Inhibitory Proteins

nork Barzi, Mercedes, Kostrz, Dorota, Menendez, Anghara, Pons, Sebastian
Argitaratua 2011

In Situ Liver Expression of HBsAg/CD3-Bispecific Antibodies for HBV Immunotherapy

nork Kruse, Robert L., Shum, Thomas, Legras, Xavier, Barzi, Mercedes, Pankowicz, Frank P., Gottschalk, Stephen, Bissig, Karl-Dimiter
Argitaratua izan da Mol Ther Methods Clin Dev (2017)

P450-Humanized and Human Liver Chimeric Mouse Models for Studying Xenobiotic Metabolism and Toxicity

nork Bissig, Karl-Dimiter, Han, Weiguo, Barzi, Mercedes, Kovalchuk, Nataliia, Ding, Liang, Fan, Xiaoyu, Pankowicz, Francis P., Zhang, Qing-Yu, Ding, Xinxin
Argitaratua izan da Drug Metab Dispos (2018)

Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine

nork MacKenzie, Kevin R., Zhao, Mingkun, Barzi, Mercedes, Wang, Jin, Bissig, Karl-Dimiter, Maletic-Savatic, Mirjana, Jung, Sung Yun, Li, Feng
Argitaratua izan da Eur J Pharm Sci (2020)

A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism

nork Barzi, Mercedes, Pankowicz, Francis P., Zorman, Barry, Liu, Xing, Legras, Xavier, Yang, Diane, Borowiak, Malgorzata, Bissig-Choisat, Beatrice, Sumazin, Pavel, Li, Feng, Bissig, Karl-Dimiter
Argitaratua izan da Nat Commun (2017)

Erratum: A novel humanized mouse lacking murine p450 oxidoreductase for studying human drug metabolism

nork Barzi, Mercedes, Pankowicz, Francis P., Zorman, Barry, Liu, Xing, Legras, Xavier, Yang, Diane, Borowiak, Malgorzata, Bissig-Choisat, Beatrice, Sumazin, Pavel, Li, Feng, Bissig, Karl-Dimiter
Argitaratua izan da Nat Commun (2017)

A hepatitis B virus transgenic mouse model with a conditional, recombinant, episomal genome

nork Kruse, Robert L., Barzi, Mercedes, Legras, Xavier, Pankowicz, Francis P., Furey, Nika, Liao, Lan, Xu, Janming, Bissig-Choisat, Beatrice, Slagle, Betty L., Bissig, Karl-Dimiter
Argitaratua izan da JHEP Rep (2021)

HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice

nork Kruse, Robert L., Shum, Thomas, Tashiro, Haruko, Barzi, Mercedes, Yi, Zhongzhen, Whitten-Bauer, Christina, Legras, Xavier, Bissig-Choisat, Beatrice, Garaigorta, Urtzi, Gottschalk, Stephen, Bissig, Karl-Dimiter
Argitaratua izan da Cytotherapy (2018)

Targeting the Apoa1 locus for liver-directed gene therapy

nork De Giorgi, Marco, Li, Ang, Hurley, Ayrea, Barzi, Mercedes, Doerfler, Alexandria M., Cherayil, Nikitha A., Smith, Harrison E., Brown, Jonathan D., Lin, Charles Y., Bissig, Karl-Dimiter, Bao, Gang, Lagor, William R.
Argitaratua izan da Mol Ther Methods Clin Dev (2021)

Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia

nork Pankowicz, Francis P., Barzi, Mercedes, Legras, Xavier, Hubert, Leroy, Mi, Tian, Tomolonis, Julie A., Ravishankar, Milan, Sun, Qin, Yang, Diane, Borowiak, Malgorzata, Sumazin, Pavel, Elsea, Sarah H., Bissig-Choisat, Beatrice, Bissig, Karl-Dimiter
Argitaratua izan da Nat Commun (2016)

Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing

nork Pankowicz, Francis P, Barzi, Mercedes, Kim, Kang Ho, Legras, Xavier, Martins, Celeste Santos, Wooton-Kee, Clavia Ruth, Lagor, William R., Marini, Juan C, Elsea, Sarah H, Bissig-Choisat, Beatrice, Moore, David D, Bissig, Karl-Dimiter
Argitaratua izan da Gastroenterology (2018)

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

nork Bissig-Choisat, Beatrice, Wang, Lili, Legras, Xavier, Saha, Pradip K., Chen, Leon, Bell, Peter, Pankowicz, Francis P., Hill, Matthew C., Barzi, Mercedes, Leyton, Claudia Kettlun, Leung, Hon-Chiu Eastwood, Kruse, Robert L., Himes, Ryan W., Goss, John A., Wilson, James M., Chan, Lawrence, Lagor, William R., Bissig, Karl-Dimiter
Argitaratua izan da Nat Commun (2015)

A human liver chimeric mouse model for non-alcoholic fatty liver disease

nork Bissig-Choisat, Beatrice, Alves-Bezerra, Michele, Zorman, Barry, Ochsner, Scott A., Barzi, Mercedes, Legras, Xavier, Yang, Diane, Borowiak, Malgorzata, Dean, Adam M., York, Robert B., Galvan, N. Thao N., Goss, John, Lagor, William R., Moore, David D., Cohen, David E., McKenna, Neil J., Sumazin, Pavel, Bissig, Karl-Dimiter
Argitaratua izan da JHEP Rep (2021)

Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer

nork Bissig-Choisat, Beatrice, Kettlun-Leyton, Claudia, Legras, Xavier D., Zorman, Barry, Barzi, Mercedes, Chen, Leon L., Amin, Mansi D., Huang, Yung-Hsin, Pautler, Robia G., Hampton, Oliver A., Prakash, Masand M., Yang, Diane, Borowiak, Malgorzata, Muzny, Donna, Doddapaneni, Harsha Vardhan, Hu, Jianhong, Shi, Yan, Gaber, M. Waleed, Hicks, M. John, Thompson, Patrick A., Lu, Yiling, Mills, Gordon B., Finegold, Milton, Goss, John A., Parsons, D. Williams, Vasudevan, Sanjeev A., Sumazin, Pavel, López-Terrada, Dolores, Bissig, Karl-Dimiter
Argitaratua izan da J Hepatol (2016)