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Targeting the checkpoint kinase Chk1 in cancer therapy

A paramount objective of the eukaryotic cell division cycle is to overcome numerous internal and external insults to faithfully duplicate the genetic information once per every cycle. This is carried out by elaborate networks of genome surveillance signaling pathways, termed replication checkpoints....

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Autors principals: Merry, Callie, Fu, Kang, Wang, Jingna, Yeh, I-Ju, Zhang, Youwei
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048588/
https://ncbi.nlm.nih.gov/pubmed/20023404
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