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Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange
A complete understanding of the molecular mechanisms underlying the functioning of large, multiprotein complexes requires experimental tools capable of simultaneously visualizing molecular architecture and enzymatic activity in real time. We developed a novel single-molecule assay that combines the...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048139/ https://ncbi.nlm.nih.gov/pubmed/21245349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018824108 |
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