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Single-molecule visualization of fast polymerase turnover in the bacterial replisome

The Escherichia coli DNA replication machinery has been used as a road map to uncover design rules that enable DNA duplication with high efficiency and fidelity. Although the enzymatic activities of the replicative DNA Pol III are well understood, its dynamics within the replisome are not. Here, we...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lewis, Jacob S, Spenkelink, Lisanne M, Jergic, Slobodan, Wood, Elizabeth A, Monachino, Enrico, Horan, Nicholas P, Duderstadt, Karl E, Cox, Michael M, Robinson, Andrew, Dixon, Nicholas E, van Oijen, Antoine M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419744/
https://ncbi.nlm.nih.gov/pubmed/28432790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23932
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