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Single-molecule studies of polymerase dynamics and stoichiometry at the bacteriophage T7 replication machinery

Replication of DNA plays a central role in transmitting hereditary information from cell to cell. To achieve reliable DNA replication, multiple proteins form a stable complex, known as the replisome, enabling them to act together in a highly coordinated fashion. Over the past decade, the roles of th...

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Main Authors: Geertsema, Hylkje J., Kulczyk, Arkadiusz W., Richardson, Charles C., van Oijen, Antoine M.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964090/
https://ncbi.nlm.nih.gov/pubmed/24591606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402010111
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