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Coupling dTTP Hydrolysis with DNA Unwinding by the DNA Helicase of Bacteriophage T7

The DNA helicase encoded by gene 4 of bacteriophage T7 assembles on single-stranded DNA as a hexamer of six identical subunits with the DNA passing through the center of the toroid. The helicase couples the hydrolysis of dTTP to unidirectional translocation on single-stranded DNA and the unwinding o...

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Detalhes bibliográficos
Main Authors: Satapathy, Ajit K., Kulczyk, Arkadiusz W., Ghosh, Sharmistha, van Oijen, Antoine M., Richardson, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190778/
https://ncbi.nlm.nih.gov/pubmed/21840995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.283796
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