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Residues in the central β-hairpin of the DNA helicase of bacteriophage T7 are important in DNA unwinding

The ring-shaped helicase of bacteriophage T7 (gp4), the product of gene 4, has basic β-hairpin loops lining its central core where they are postulated to be the major sites of DNA interaction. We have altered multiple residues within the β-hairpin loop to determine their role during dTTPase-driven D...

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Bibliographische Detailangaben
Hauptverfasser: Satapathy, Ajit K., Kochaniak, Anna B., Mukherjee, Sourav, Crampton, Donald J., van Oijen, Antoine, Richardson, Charles C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872414/
https://ncbi.nlm.nih.gov/pubmed/20351255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002734107
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