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Heterohexamer of 56- and 63-kDa Gene 4 Helicase-Primase of Bacteriophage T7 in DNA Replication

Bacteriophage T7 expresses two forms of gene 4 protein (gp4). The 63-kDa full-length gp4 contains both the helicase and primase domains. T7 phage also express a 56-kDa truncated gp4 lacking the zinc binding domain of the primase; the protein has helicase activity but no DNA-dependent primase activit...

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Détails bibliographiques
Auteurs principaux: Zhang, Huidong, Lee, Seung-Joo, Kulczyk, Arkadiusz W., Zhu, Bin, Richardson, Charles C.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464535/
https://ncbi.nlm.nih.gov/pubmed/22887996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.401158
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