Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1

Genetic studies indicate that the enzyme pteridine reductase 1 (PTR1) is essential for the survival of the protozoan parasite Trypanosoma brucei. Herein, we describe the development and optimisation of a novel series of PTR1 inhibitors, based on benzo[d]imidazol-2-amine derivatives. Data are reporte...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Spinks, Daniel, Ong, Han B, Mpamhanga, Chidochangu P, Shanks, Emma J, Robinson, David A, Collie, Iain T, Read, Kevin D, Frearson, Julie A, Wyatt, Paul G, Brenk, Ruth, Fairlamb, Alan H, Gilbert, Ian H
格式: Artigo
語言:Inglês
出版: WILEY-VCH Verlag 2011
主題:
Full Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047710/
https://ncbi.nlm.nih.gov/pubmed/21275054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201000450
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍