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HMGB1 Acts on Microglia Mac1 to Mediate Chronic Neuroinflammation That Drives Progressive Neurodegeneration

What drives the gradual degeneration of dopamine neurons in Parkinson's disease (PD), the second most common neurodegenerative disease, remains elusive. Here, we demonstrated, for the first time, that persistent neuroinflammation was indispensible for such a neurodegenerative process. 1-Methyl-...

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Bibliografske podrobnosti
Main Authors: Gao, Hui-Ming, Zhou, Hui, Zhang, Feng, Wilson, Belinda C., Kam, Wayneho, Hong, Jau-Shyong
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046932/
https://ncbi.nlm.nih.gov/pubmed/21248133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3732-10.2011
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