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HMGB1 Acts on Microglia Mac1 to Mediate Chronic Neuroinflammation That Drives Progressive Neurodegeneration

What drives the gradual degeneration of dopamine neurons in Parkinson's disease (PD), the second most common neurodegenerative disease, remains elusive. Here, we demonstrated, for the first time, that persistent neuroinflammation was indispensible for such a neurodegenerative process. 1-Methyl-...

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Detalhes bibliográficos
Main Authors: Gao, Hui-Ming, Zhou, Hui, Zhang, Feng, Wilson, Belinda C., Kam, Wayneho, Hong, Jau-Shyong
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046932/
https://ncbi.nlm.nih.gov/pubmed/21248133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3732-10.2011
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