HMGB1 Acts on Microglia Mac1 to Mediate Chronic Neuroinflammation That Drives Progressive Neurodegeneration

What drives the gradual degeneration of dopamine neurons in Parkinson's disease (PD), the second most common neurodegenerative disease, remains elusive. Here, we demonstrated, for the first time, that persistent neuroinflammation was indispensible for such a neurodegenerative process. 1-Methyl-...

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Détails bibliographiques
Auteurs principaux: Gao, Hui-Ming, Zhou, Hui, Zhang, Feng, Wilson, Belinda C., Kam, Wayneho, Hong, Jau-Shyong
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2011
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046932/
https://ncbi.nlm.nih.gov/pubmed/21248133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3732-10.2011
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