HMGB1 Acts on Microglia Mac1 to Mediate Chronic Neuroinflammation That Drives Progressive Neurodegeneration

What drives the gradual degeneration of dopamine neurons in Parkinson's disease (PD), the second most common neurodegenerative disease, remains elusive. Here, we demonstrated, for the first time, that persistent neuroinflammation was indispensible for such a neurodegenerative process. 1-Methyl-...

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Autori principali: Gao, Hui-Ming, Zhou, Hui, Zhang, Feng, Wilson, Belinda C., Kam, Wayneho, Hong, Jau-Shyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046932/
https://ncbi.nlm.nih.gov/pubmed/21248133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3732-10.2011
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