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Locus coeruleus neurons are most sensitive to chronic neuroinflammation-induced neurodegeneration

Parkinson’s disease (PD) develops over decades through spatiotemporal stages that ascend from the brainstem to the forebrain. The mechanism behind this caudo-rostral neurodegeneration remains largely undefined. In unraveling this phenomenon, we recently developed a lipopolysaccharide (LPS)-elicited...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Wang, Qingshan, Oyarzabal, Esteban A., Song, Sheng, Wilson, Belinda, Santos, Janine H., Hong, Jau-Shyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316605/
https://ncbi.nlm.nih.gov/pubmed/31923552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.01.003
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