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Loss of brain norepinephrine elicits neuroinflammation-mediated oxidative injury and selective caudo-rostral neurodegeneration

Environmental toxicant exposure has been strongly implicated in the pathogenesis of Parkinson’s disease (PD). Clinical manifestations of non-motor and motor symptoms in PD stem from decades of progressive neurodegeneration selectively afflicting discrete neuronal populations along a caudo-rostral ax...

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Détails bibliographiques
Publié dans:Mol Neurobiol
Auteurs principaux: Song, Sheng, Jiang, Lulu, Oyarzabal, Esteban A., Wilson, Belinda, Li, Zibo, Shih, Yen-Yu Ian, Wang, Qingshan, Hong, Jau-Shyong
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348128/
https://ncbi.nlm.nih.gov/pubmed/30051353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1235-1
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