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Highly Enantioselective Mannich Reactions with α-Aryl Silyl Ketene Acetals and Imines

[Image: see text] Mannich reactions with chiral silicon Lewis acid-activated acylhydrazones and α-aryl silyl ketene acetals and α-aryl, α-alkyl silyl ketene imines proceed efficiently and with good to excellent levels of both diastereoselectivity and enantioselectivity. The reactions provide access...

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Detalles Bibliográficos
Main Authors: Notte, Gregory T., Baxter Vu, Jenny M., Leighton, James L.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042282/
https://ncbi.nlm.nih.gov/pubmed/21235253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol103096u
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