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Connective synthesis of 5,5-disubstituted hydantoins by tandem α-amination and α-arylation of silyl ketene acetals

5,5-Disubstituted hydantoins, formally the cyclisation products of quaternary amino acids, were formed connectively from simple ester-derived starting materials by a one-pot tandem method. Amination of the silyl ketene acetal derivative of a methyl ester takes place by silver-catalysed addition to t...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Saunthwal, Rakesh K., Cornall, Matthew T., Abrams, Roman, Ward, John W., Clayden, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429467/
https://ncbi.nlm.nih.gov/pubmed/30996929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05263h
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