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Cu-Catalyzed Enantioselective Allylic Alkylation with a γ-Butyrolactone-Derived Silyl Ketene Acetal.

Herein, we report a Cu-catalyzed enantioselective allylic alkylation using a γ-butyrolactone-derived silyl ketene acetal. Critical to the development of this work was the identification of a novel mono-picolinamide ligand with the appropriate steric and electronic properties to afford the desired pr...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Jette, Carina I., Tong, Z. Jaron, Hadt, Ryan G., Stoltz, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051182/
https://ncbi.nlm.nih.gov/pubmed/31742854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201912618
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