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Enantioselective Synthesis of Dialkylated N-Heterocycles by Palladium-Catalyzed Allylic Alkylation

The enantioselective synthesis of α-disubstituted N-heterocyclic carbonyl compounds has been accomplished using palladium-catalyzed allylic alkylation. These catalytic conditions enable access to various heterocycles, such as morpholinone, thiomorpholinone, oxazolidin-4-one, 1,2-oxazepan-3-one, 1,3-...

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Bibliografiska uppgifter
I publikationen:Org Lett
Huvudupphovsmän: Numajiri, Yoshitaka, Jiménez-Osés, Gonzalo, Wang, Bo, Houk, K. N., Stoltz, Brian M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410707/
https://ncbi.nlm.nih.gov/pubmed/25714704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol503425t
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