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SARs at the Monoamine Transporters for a Novel Series of Modafinil Analogues

[Image: see text] A series of modafinil (1) analogues were synthesized wherein (1) para-halo-substitutents were added to the aryl rings, (2) the sulfoxide function was removed, and (3) the primary amide group was replaced with secondary and tertiary amides and amines to investigate the effects of th...

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Autors principals: Cao, Jianjing, Prisinzano, Thomas E., Okunola, Oluyomi M., Kopajtic, Theresa, Shook, Matthew, Katz, Jonathan L., Newman, Amy Hauck
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2010
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041981/
https://ncbi.nlm.nih.gov/pubmed/21344069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1002025
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