MCL-1 localizes to sites of DNA damage and regulates DNA damage response

MCL-1, a pro-survival member of the BCL-2 family, was previously shown to have functions in ATR-dependent Chk1 phosphorylation following DNA damage. To further delineate these functions, we explored possible differences in DNA damage response caused by lack of MCL-1 in mouse embryo fibroblasts (MEFs...

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Detaylı Bibliyografya
Asıl Yazarlar: Jamil, Sarwat, Stoica, Cezar, Hackett, Tillie-Louise, Duronio, Vincent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2010
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040962/
https://ncbi.nlm.nih.gov/pubmed/20647761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.14.12354
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