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MCL-1 localizes to sites of DNA damage and regulates DNA damage response
MCL-1, a pro-survival member of the BCL-2 family, was previously shown to have functions in ATR-dependent Chk1 phosphorylation following DNA damage. To further delineate these functions, we explored possible differences in DNA damage response caused by lack of MCL-1 in mouse embryo fibroblasts (MEFs...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Landes Bioscience
2010
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040962/ https://ncbi.nlm.nih.gov/pubmed/20647761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.14.12354 |
| Tagiau: |
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