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Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage
BACKGROUND: The DNA-dependent protein kinase (DNA-PK) is a nuclear complex composed of a large catalytic subunit (DNA-PKcs) and a heterodimeric DNA-targeting subunit Ku. DNA-PK is a major component of the non-homologous end-joining (NHEJ) repair mechanism, which is activated in the presence of DNA d...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3316135/ https://ncbi.nlm.nih.gov/pubmed/22404984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-13-7 |
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