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The Cellular Control of DNA Double-Strand Breaks

DNA double-strand breaks (DSBs) are the most hazardous lesions arising in the genome of eukaryotic organisms, and yet occur normally during DNA replication, meiosis, and immune system development. The efficient repair of DSBs is crucial in maintaining genomic integrity, cellular viability, and the p...

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Bibliographic Details
Main Authors: Scott, Shaun P., Pandita, Tej K.
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088996/
https://ncbi.nlm.nih.gov/pubmed/16927314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21067
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