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MCL-1 localizes to sites of DNA damage and regulates DNA damage response
MCL-1, a pro-survival member of the BCL-2 family, was previously shown to have functions in ATR-dependent Chk1 phosphorylation following DNA damage. To further delineate these functions, we explored possible differences in DNA damage response caused by lack of MCL-1 in mouse embryo fibroblasts (MEFs...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Landes Bioscience
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040962/ https://ncbi.nlm.nih.gov/pubmed/20647761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.14.12354 |
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