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Analysis of the stabilities of hexameric amyloid-β (1–42) models using Discrete Molecular Dynamics simulations
Amyloid-β (Aβ) oligomers appear to play a pivotal role in Alzheimer’s disease. A 42 residue long alloform, Aβ42, is closely related to etiology of the disease. In vitro results show evidences of hexamers; however structures of these hexamers have not been resolved experimentally. Here, we use Discre...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040446/ https://ncbi.nlm.nih.gov/pubmed/21186130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2010.11.008 |
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