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Molecular Dynamics Simulations of Amyloid β-Peptide (1-42): Tetramer Formation and Membrane Interactions

The aggregation cascade and peptide-membrane interactions of the amyloid β-peptide (Aβ) have been implicated as toxic events in the development and progression of Alzheimer’s disease. Aβ(42) forms oligomers and ultimately plaques, and it has been hypothesized that these oligomeric species are the ma...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Brown, Anne M., Bevan, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018154/
https://ncbi.nlm.nih.gov/pubmed/27602722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.08.001
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