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Side-Chain Interactions Determine Amyloid Formation by Model Polyglutamine Peptides in Molecular Dynamics Simulations
The pathological manifestation of nine hereditary neurodegenerative diseases is the presence within the brain of aggregates of disease-specific proteins that contain polyglutamine tracts longer than a critical length. To improve our understanding of the processes by which polyglutamine-containing pr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1471860/ https://ncbi.nlm.nih.gov/pubmed/16565057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.079269 |
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