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Side-Chain Interactions Determine Amyloid Formation by Model Polyglutamine Peptides in Molecular Dynamics Simulations

The pathological manifestation of nine hereditary neurodegenerative diseases is the presence within the brain of aggregates of disease-specific proteins that contain polyglutamine tracts longer than a critical length. To improve our understanding of the processes by which polyglutamine-containing pr...

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Bibliografski detalji
Glavni autori: Marchut, Alexander J., Hall, Carol K.
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1471860/
https://ncbi.nlm.nih.gov/pubmed/16565057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.079269
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