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Molecular Dynamics Simulations of Amyloid β-Peptide (1-42): Tetramer Formation and Membrane Interactions

The aggregation cascade and peptide-membrane interactions of the amyloid β-peptide (Aβ) have been implicated as toxic events in the development and progression of Alzheimer’s disease. Aβ(42) forms oligomers and ultimately plaques, and it has been hypothesized that these oligomeric species are the ma...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Brown, Anne M., Bevan, David R.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018154/
https://ncbi.nlm.nih.gov/pubmed/27602722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.08.001
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