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Molecular Mechanism and Kinetics of Amyloid-β42 Aggregate Formation: A Simulation Study

As an important neuropathological hallmark of Alzheimer’s disease (AD), the oligomerization of amyloid-β (Aβ) peptides has been intensively investigated in both theoretical and experimental studies. However, the oligomerization space in term of the kinetics, molecular mechanism and the oligomer stru...

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Pubblicato in:ACS Chem Neurosci
Autori principali: Man, Viet Hoang, He, Xibing, Ji, Beihong, Liu, Shuhan, Xie, Xiang-Qun, Wang, Junmei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336531/
https://ncbi.nlm.nih.gov/pubmed/31660732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00473
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